Human Material Research

Documentation Required

Work with unfixed human materials, like human cell lines, requires the following:

1. Safer Sharps Evaluation Form (PDF)

Sharps: needles, scalpels, Pasteur pipettes must have safety mechanisms and personnel implementing them must have proper training in their use. Making sure that the safety device is not chosen based on cost or convenience, it is important to have all personnel using the device fill out an evaluation form. 

2. Safer Sharps Annual Review Form (DOC)

An annually updated list of all sharps used in the lab is required (annual review form) with a justification if they do not have a safety mechanism. An example of a justification would be “No use with human materials” or “No safety mechanism alternative available.”

3. Source Protocol (PDF)

Source protocols are required if the source of the human material can be identified and contacted. If the sample is de-identified, then this is not required. Please see the MSU Exposure Control Plan (PDF) for more information on how to create a source protocol.

4. Task Procedure (DOCX) (Standard Operating Procedure)

Task procedures are standard operating procedures for tasks that are hazardous. Personnel should be familiar with these documents listing the biohazard, engineering controls, work practices, personal protective equipment, disinfection, decontamination and waste management of hazardous procedures in their lab. An example can be found in the MSU Exposure Control Plan (PDF).

5. Biological Inventory (XLSX)

Inventory the biological material in the lab and update it frequently. This is for EHS to know what you are working with and what is in the lab, but more importantly, for you to be able to use in case of events like freezer malfunction, vandalism, theft, or other catastrophes. More information can be found in the MSU Biosafety Manual (PDF).

6. Biosafety Registration

EHS uses the Biosafety Registration to help direct you to the correct training, as well as other required documents. This document is required by MSU's Institutional Biosafety Committee (IBC).

7. Site-Specific Training Checklist (PDF)

Site-specific training checklists are to be reviewed and filled out annually. This is a guide to be used to help make the online general safety trainings applicable to your facility and the specific hazards your personnel will work with. This should include going over all the task procedures, safer sharps and personnel protective equipment. All personnel in the lab will be required to have a signature on file for this document every year.

For More Information

For more information, refer to the MSU Exposure Control Plan (PDF) or the MSU Biosafety Manual (PDF).